Introduction
The GRC on Cyclic Nucleotide PDEs has a long and storied history, and engages investigators whose research covers the entire phosphodiesterases (PDE) superfamily. In addition to presentations on novel assessments of PDE compartmentalized--targeting of cyclic nucleotides and related signaling, we progress through all the PDEs from 1 to 11, with leading research presented for each. Day one deals with basic principals and novel subcellular molecular tracking of cyclic nucleotide signaling and compartmentation. Day 2 starts with PDE1 and we move sequentially through to PDE11 by the end of the weeklong conference. Speakers will focus on general molecular and signaling aspects of PDEs and explore the role of various PDES in contributing to major diseases and identify novel therapeutic roles for their pharmacological modulation.
Call for paper
Important date
The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by February 12, 2016. Please check back for updates.
- Non-Canonical Cyclic Nucleotides and Protein Regulators
(David Kass / Thomas Brand / Roland Seifert) - Imaging Cyclic Nucleotide/Effector Kinase Nano-Domains
(Choel Kim / Manuela Zaccolo / Viacheslav Nikolaev / Jin Zhang) - New Insights into the Control of Cyclic AMP
(William Catterall / Carmen Dessaur / John Scott / Chen Yan / Scott Soderling / Joseph Beavo) - PDE Regulatory Interactions with Receptors and Kinases
(Emilio Hirsch / Yang Xiang / Gregoire Vandecasteele / Yassine Sassi / Alessandra Ghigo) - Role of PDE1 and PDE2 in Cardiac, Pulmonary, and Neurological Diseases
(Kjetil Tasken / Lawrence Wennogle / Ali El-Armouche / Ying Xu / Adrian Hobbs) - PDE3 and PDE4: Vascular Disease and Inflammation
(Veronique Leblais / Silvia Bahring / Vincent Manganiello / Jian-Dong Li / Donald Maurice) - Regulation of PDE4 Signaling and PDE5-Inhibition for Duchene Muscular Dystrophy
(Susan Taylor / Marco Conti / George Baillie / Miles Houslay / Ronald Victor) - Neurological Role for PDEs: Therapeutic Implications
(Eva Degerman / Nikolai Artemyev / Ana Perez-Castillo / Cornelia Dorner-Ciossek / Michael Russwurm) - PDEs and the Central Nervous System
(Christopher Schmidt / Liliana Castro / Nick Brandon / Michy Kelly)
All Comments
Important Date
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Conference Date
Jun 12
2016
toJun 17
2016
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May 12 2016
Final Paper Deadline
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Jun 17 2016
Registration deadline
Contact Information
- Gordon Research Conference
- 401*********
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